Gabapentin side effects?

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moosedrool

Trad climber
lost, far away from Poland
Topic Author's Original Post - Apr 5, 2013 - 05:36pm PT
Anybody taking it?

It helps me BIG time, but it also makes me:

 light headed

 my IQ dropped by 30 points (estimated by stupid me)

 horny (lol, I feel like a teenager in that department, embarrassing but a nice feeling for an almost 59 years old fart)

P.S. I will probably regret posting all of this, but I am heavily medicated and don't care :)


High Fructose Corn Spirit

Gym climber
Potemkin Village
Apr 5, 2013 - 05:38pm PT
http://en.wikipedia.org/wiki/Gabapentin

"Gabapentin has been associated with an increased risk of suicidal acts or violent deaths."
DanaB

climber
CT
Apr 5, 2013 - 05:44pm PT
The package inserts of all prescription medications are available online. Drugs.com is also a reliable source.
moosedrool

Trad climber
lost, far away from Poland
Topic Author's Reply - Apr 5, 2013 - 05:46pm PT
HFCS, of course I am familiar with the drug and its side effects.

Just curious if anybody here has similar experience...


"Gabapentin has been associated with an increased risk of suicidal acts or violent deaths."

What does it mean "violent deaths"?
Tarbuster

climber
right here, right now
Apr 5, 2013 - 05:48pm PT
Gabapentin a.k.a. Neurontin.
I was on it over a month or so for nerve pain related to a herniated disk in my neck. Still couldn't use the affected arm for the whole month and it was pretty painful when I tried; then did two rounds of guided fluoroscopy cortisone which fixed me up much better.

The MD said that side effects from Gabapentin would be minimal as in maybe a little forgetfulness. I had no side effects.
apogee

climber
Technically expert, safe belayer, can lead if easy
Apr 5, 2013 - 06:15pm PT
I had a very similar condition- herniated disc at C6/7, with lots of nerve pain in my arm. Gabapentin didn't do much of anything for me- good or bad- just didn't work for me. I gave up on it.

I tried the cortisone injection- that helped for about a day or two, and the pain came right back. Relief only came from surgery- posterior foraminotomy- and it happened almost immediately.
Naitch

climber
Seneca area
Apr 5, 2013 - 06:24pm PT
Given to me by my doc for 4 months hoping it would help a prevent a bad case of lingering pain following shingles (post hepatic neuralgia) but didn't do sh#t! I wasn't aware of the potential negative side effects.
Norton

Social climber
the Wastelands
Apr 5, 2013 - 06:25pm PT
Yeah, I have been on gab for years

It "retards" the firing of nerve endings, among other things

most people who "try" it don't take anywhere near a high enough daily dosage and don't stay on it long enough to build in the body so it actually starts to take effect and reduce mostly nerve pain

as such it is systemic and needs to bind on itself over time
Naitch

climber
Seneca area
Apr 5, 2013 - 06:27pm PT
What does "stay on it long enough" mean? How long?
MH2

climber
Apr 5, 2013 - 06:27pm PT
Moosedrool,

Perhaps you will understand if I tell you it turned my next door neighbor from a Prussian into a Slovenian, or maybe a Samoan.
Norton

Social climber
the Wastelands
Apr 5, 2013 - 06:32pm PT
at least two months

Adult Dosing
Gabapentin is started at low doses (100 mg to 300 mg total daily) and increased by 100 300 mg every 1-3 days to effect. A typical schedule might be: day 1-2: 300 mg nightly; day 3-4: 300 mg twice daily; day 5-7: 600 mg twice daily; day 8 onwards: 600 mg three times a day. The usual effective total daily dose is 900-3600 mg, administered in three divided doses per day. Higher doses may be needed. Titration should proceed more slowly in elderly patients.
Josh Higgins

Trad climber
San Diego
Apr 5, 2013 - 06:35pm PT
Adverse Reactions/Side Effects

CNS: SUICIDAL THOUGHTS, confusion, , depression, drowsiness, sedation, anxiety, concentration difficulties (children), dizziness, emotional lability (children), hostility, hyperkinesia (children), malaise, vertigo, weakness.

EENT: abnormal vision, nystagmus.

CV: hypertension.

GI: weight gain, anorexia, flatulence, gingivitis.

MS: arthralgia.

Neuro: ataxia, altered reflexes, hyperkinesia, paresthesia.

Misc: MULTI-ORGAN HYPERSENSITIVITY REACTIONS, facial edema.

*CAPITALS indicates life-threatening.
Naitch

climber
Seneca area
Apr 5, 2013 - 06:38pm PT
Hmmm...guess maybe it just didn't work for me as I was on as high a dose as my doc was comfortable giving me and never noticed any lessing of the pain after 4 months, so finally just stopped. Pain has gradually lessened on it's own but still significant enough pain in the shoulder to hinder climbing, damnit! Glad I didn't experience any of the side effects mentioned except the horniness. That one might have been more interesting and appreciated at 62.
Big Mike

Trad climber
BC
Apr 5, 2013 - 06:47pm PT
Interesting. I'm on pregabalin right now as well as my hydromorphone. They want to switch me over to gaba if i still need a nerve pain killer because it's cheaper. I'm having second thoughts now.... Hopefully i just don't need the sh#t anymore..
mucci

Trad climber
The pitch of Bagalaar above you
Apr 5, 2013 - 06:49pm PT
Wanted to kill myself on that sh#t.

No amount of pain was worth dealing with that.

Hope it goes better for you...
FTOR

Sport climber
CA
Apr 5, 2013 - 06:55pm PT
there's a type of it that goes by the trade name gralise. ramps up much quicker to an effective dose. no personal experience with it, probably costs a lot.
Tarbuster

climber
right here, right now
Apr 5, 2013 - 06:55pm PT
I see potential here!
This could become the "Friday Night While Posting on Non-Recreational Pharmaceuticals Thread".
Naitch

climber
Seneca area
Apr 5, 2013 - 07:02pm PT
Personally, since Gabapentin didn't do anything for me, I'm thinking of going back on the lettuce to see if that helps or not.
moosedrool

Trad climber
lost, far away from Poland
Topic Author's Reply - Apr 5, 2013 - 07:03pm PT
Gabapentin completely eliminated the pain from shingles for me. In addition, I don't experience any pain from neuralgia anymore or sharp shooting pains in my injured foot. And, I can finally sleep at night! It doesn't relief the "oridinary" pain because it is not its indication.

So, apart from the strange side effects, it is a wanderful medication for me.

Taking 600mg every 8 hours.

Now, about those BOOBS...

;)

Edit: The lettuce gave me horrors. I hate it. NEVER want to smoke it again. Probably the most horrific experience I ever had. 0_0
Norton

Social climber
the Wastelands
Apr 5, 2013 - 07:11pm PT
Taking 600mg every 8 hours.

good dosage

like I said, most people do not get prescribed a high enough dosage to do much at all
Big Mike

Trad climber
BC
Apr 5, 2013 - 07:13pm PT
Moose, did you cross it with your other drugs? If so it can be really bad yes.
I've found eating it in small amounts has been super helpfull in figuring out how my new body arrangement works.
Naitch

climber
Seneca area
Apr 5, 2013 - 07:24pm PT
Glad it's working for you Moose. 7 months on for me since I had shingles and it's still going (the neuralgia), though much less than at first. I was on a dose at least that strong and nothing. Guess it goes to show how people react differently to different substances. And I'm a skinny little dude too and am usually sensitive to normal doses of thing. Nothing but good experiences with the lettuce, but then I never partook for pain before.
Big Mike

Trad climber
BC
Apr 5, 2013 - 07:29pm PT
Naitch try eating it for pain.. Butter style
moosedrool

Trad climber
lost, far away from Poland
Topic Author's Reply - Apr 5, 2013 - 07:30pm PT
Mike, it actually enhanced the action of oxycodone. I lower the dose of oxycodone significantly and it still worked. I went from 6X5mg to 1X2.5mg a day within a week. Haven't noticed any cross reaction with ibuprofen or acetaminophen.
healyje

Trad climber
Portland, Oregon
Apr 5, 2013 - 07:30pm PT
Yeah, my wife has been on it for the past three weeks - a real life saver in our case. Backed her down from the hairy edge of pain to where she could cope again and that was on just 300mg a day. She's between surgeries at the moment and we're working her up to 900mg / day which should lock her in so she can get through it all for the next couple of months.

Saw the pain doc yesterday, he was saying you could down 10,000mgs of the stuff with a glass of water, but your body can only absorb about 600-800mg max in any one shot and you'll just sh#t the rest out. Way better than the Oxycontin/Oxycodene/Soma mix.
BLUEBLOCR

Social climber
joshua tree
Apr 5, 2013 - 07:42pm PT

Perhaps you will understand if I tell you it turned my next door neighbor from a Prussian into a Slovenian, or maybe a Samoan.

Hey,, At least he's still alive! LLLLLLLOL!!!
BLUEBLOCR

Social climber
joshua tree
Apr 5, 2013 - 07:48pm PT

Adverse Reactions/Side Effects

CNS: SUICIDAL THOUGHTS, confusion, , depression, drowsiness, sedation, anxiety, concentration difficulties (children), dizziness, emotional lability (children), hostility, hyperkinesia (children), malaise, vertigo, weakness.

So,, What do U take for this? Still. LLLLLLLLOL

sorry,, i know, pains aren't funny
Naitch

climber
Seneca area
Apr 5, 2013 - 07:55pm PT
Big Mike, yeah I have a friend who's into butter. Will have to get some from him and give it a try.
john hansen

climber
Apr 5, 2013 - 07:57pm PT
Tarbuster, just had a tooth extracted a few hours ago. The put me in a semi awake state where you dont remember the surgury.
What was it that killed Michael Jackson , Propofal or something. they gave me some of that with some ketamine and some other one that started with D,,, A veritable friday after noon cocktail.

Coming out of that stuff is a trip, its like an out of body sensation where nothing exists but your mind. Had that same combo once before that was a little stronger, as I slowly came out of it I realized my mind was in a white space. I could still think enough after a while to think, Is this the reality I will exist in from now on ... after some indeterminate amount of time,, 5 minutes or 20 , who knows I realized I was looking up at a flourecent light in the dentists office.

Sorry for the thread drift, I am probably still a bit high. LOL
Naitch

climber
Seneca area
Apr 5, 2013 - 08:38pm PT
Ah...ketamine...had that stuff for wisdom teeth extraction when I was living in Papua New Guinea many years ago. Supposedly while on the stuff you want a very calm and serene environment. While I was under I got so relaxed that I swallowed my tongue (they tell me) and that caused a minor panic among those in the dental office because I couldn't breath. I went on a very, Very BAAAAD trip. Everything was a liquid thought that were occurring and flowing a zillion times a second. Seemed like I was trapped in this never ending feedback loop and would never ever get out. Took me forever to come down and seemed like I'd been "gone" 10,000 years. Dang if I was using that stuff recreationally I woulda stopped cold that moment. Bad experience. Nightmare doesn't even began to describe it. A total freakout.
Big Mike

Trad climber
BC
Apr 5, 2013 - 09:00pm PT
Damn. That's what they call the k-hole i geuss.. Nasty.

Moose i was talking about the green stuff, but damn i hate those oxy's! They messed me up bad!!
john hansen

climber
Apr 5, 2013 - 09:07pm PT
Naitch , ' in an everlasting forward loop" descibes it well. I kind of enjoyed it afterward and felt very calm during. There was no body only my "thoughts", very coherent and normal, and then my enviroment, that had no time or any thing recognizable , exept white space,"Like white noise without any sound."

There,s a quote for you
moosedrool

Trad climber
lost, far away from Poland
Topic Author's Reply - Apr 5, 2013 - 09:17pm PT
Lol Mike. I was on gabapentin only when I smoked that weed. I had a trip I wan't forget (although I can recall only pieces of it). First I had visual and audio halucinations. Then touch and taste. Wired, but not bad. After that I got scared I could lose control and do something dangerous. My short memory was gone, so I couldn't hold any thoughts except that fear. I shiver just thinking about that. SCARY!!!
Allen Hill

Social climber
CO.
Apr 5, 2013 - 09:21pm PT
Bad bad thoughts. Hope your taking it for pain.
Big Mike

Trad climber
BC
Apr 5, 2013 - 09:27pm PT
Dude! Sounds familiar except i was on 9mg of long acting hydro, 4mg of short acting (which i took all at once) and pregab that morning.. Holy sh#t bud! No hallucinations but i could hear everything that was going on in my occupational therapy all at the same time! There was 50 different conversations going on at the same time and i could differentiate each one but it was super sensory overload!

I couldn't focus on the task at hand and i just wanted to close my eyes and pass out! I was tripping balls! Then the doctors started bombarding me with the questions!! I just wanted to hide but i couldn't even leave my bed!! Talk about shitty! ;)
Tarbuster

climber
right here, right now
Apr 5, 2013 - 10:36pm PT
Golly, this really is the Friday night medication smorgasbord thread now.

I'm currently in the "dig back out of the hole" endless-physical-therapy-phase of dual hip replacement. I found Oxycodone and OxyContin perfectly livable post surgery; no problem staying clear and I think it actually improved my reading comprehension! Try that with medical marijuana, which is something more akin to reading with sandbags on your head. Either way, go for a 24-hour extraction in hot coconut oil and syringe it into capsules. Smoking just doesn't comport with medicine.

Prior to the joint replacement I tried Cymbalta for ongoing unresolved systemic/musculoskeletal pain and I could barely peel myself off the carpet. Had to back away from that stuff nice and easy.

This weekend I will begin a six-week course of a wakefulness promoting agent called Provigil to see if I can get better repair during sleep cycles. First it's gotta pull me out of my face down in the shag carpet posture and out into the sunlight. Heh. What do they know, really, when it comes down to difficult diagnoses. So many of these specialists have a hammer and see a nail!

Side effects??? The neurologist/sleep medicine Doc I'm seeing says they'd do well just to call them effects.
healyje

Trad climber
Portland, Oregon
Apr 6, 2013 - 03:01am PT
Tar: Prior to the joint replacement I tried Cymbalta for ongoing unresolved systemic/musculoskeletal pain and I could barely peel myself off the carpet. Had to back away from that stuff nice and easy.

Good to know. The pain doc mentioned it, but want to hold of and see if the Gabapentin alone wouldn't get the job done.
Tarbuster

climber
right here, right now
Apr 6, 2013 - 09:01am PT
To make this informal poll more accurate, I just recalled I did have a paradoxical effect with gabapentin.
I woke up three hours earlier every morning and felt about the same with my normal sleep regimen, which is trashed.

Tarbuster

climber
right here, right now
Apr 6, 2013 - 09:13am PT
Cymbalta is an antidepressant that is also on label for musculoskeletal pain. My interpretation is that it works well for things like fibromyalgia. My exhaustion response was an outlier.

I believe Gabapentin is in anti-spasmodic. I have guessed that it reduced all these extra contractions from my bruxism and this is why I needed less sleep.

I've trotted out both of these drug responses to doctors and often they just don't know how to comment. The doctor who prescribed Cymbalta said to me: "Well, it's a serotonin reuptake inhibitor, meaning it keeps it in your system. Apparently you don't need any more serotonin".

The sleep medicine neurologist commented on the latter: "We can't even draw such inferences, because although the drug companies want you to think these drugs target specific processes, they do all kinds of things". As to the Gabapentin reaction, he just said that I can't really draw any inferences from my need for less sleep.

In short you just can't critique these things very well from the standpoint of a layman.
Big Mike

Trad climber
BC
Apr 6, 2013 - 09:15am PT
Lol roy! I'm surprised you find the oxy ok. It really makes me dopey. That could be the fact that i'm mixing it with the pregabalin, but many people i've talked to have had similar effects. The hydromophone had been good to me besides the constipation issues.. I'm completely with it for rehab, not spacey like i was on the oxycodin. Plus it's long acting so only every 8 hours instead of waking me up every 3 hours for meds. That sucked.

They're trying to wean me off the stuff now which i agree with, but i don't want to run into pain issues again like i did a couple of weeks ago when i voluntarily tried to do the same. They ordered it be reduced and then i was hurting real good, and because they ordered it all the nurses could do was give me the short acting hydro which i hate because it makes me feel super dopey too, and gives me horrible nightmares.

I told them this time to leave the dosage alone and i would take less to figure it out for myself.
Tarbuster

climber
right here, right now
Apr 6, 2013 - 09:20am PT
Mike, I'm pretty sure most of this stuff requires a careful taper, specifically with the synthetic opiates and demonstrably so with the Cymbalta.
I've been very compliant with a nice easy taper off of all of it. I.e. a long slope out.

Heal it up BIG Mike!
Big Mike

Trad climber
BC
Apr 6, 2013 - 10:09am PT
Thanks Tar! I'm killing it so far. It sounds like you know about long roads. I'll see you on the other side brother!
Tarbuster

climber
right here, right now
Apr 6, 2013 - 10:35am PT
And Mike, you mentioned constipation with synthetic opiates.
Totally bad news. Same for most of us I would imagine. (Cymbalta did that to me as well and I now have permanent hemorrhoids from it. Ligation failed; I don't know why gastroenterologists even bother).

I found excellent results with Senna:sennosides 8.6 mg, a natural laxative. Two per day. Even with one Vicodin I would take a Senna.
Also followed that up with the standard cap-full dose of polyethylene glycol 3350. Once per day.

Not sure why they like to recommend milk of magnesia: that stuff just gunks up my stomach. Okay, back to the Saturday morning funny papers.
Big Mike

Trad climber
BC
Apr 6, 2013 - 10:39am PT
I've been having decent results with prune juice, and they give me cynacide or something. But since easter the chocolate intake has seemed to make things pretty smooth. Or better at least. I'll look into your suggestions though.

Ya the peg does ok too. I'm not super fond of how gassy it makes me..
MH2

climber
Apr 6, 2013 - 11:08am PT
they give me cynacide or something


Same thing Tarbuster mentioned: sennoside
Big Mike

Trad climber
BC
Apr 6, 2013 - 11:11am PT
Right. I like chocolate better tho.. ;)
Big Mike

Trad climber
BC
Apr 6, 2013 - 12:42pm PT
Mcdonalds seems to work pretty damn good too.. ;)

Good thing i have an appointment with my pharmacist next week to learn more about these drugs i'm taking.... I'm pretty clueless so far.. "Is that the little orange round one?" ;)
moosedrool

Trad climber
lost, far away from Poland
Topic Author's Reply - Apr 6, 2013 - 01:55pm PT
I am also trying to figure out whether icing is really helpful.

Conventional wisdom says yes, but I am not so sure. It limits blood supply, so the haeling process is altered.

Very confusing.

Ibuprofen is bad, that's a fact.
Big Mike

Trad climber
BC
Apr 6, 2013 - 02:03pm PT
If it's swollen, yes icing is helpful. The key is to limit the amount you do it. 20 mins or so every 3 to 4 hours. If you're worried about blood flow, hot and cold contrast can be an excellent solution as well, after the first 48 hours.
Hankster

Social climber
Golden, CO
Apr 6, 2013 - 02:03pm PT
I see potential here!
This could become the "Friday Night While Posting on Non-Recreational Pharmaceuticals Thread".

HAHAHAHAHA.. That's boss Roy! I was sleeping with Dr. Trazadone when this thread took off.
healyje

Trad climber
Portland, Oregon
Apr 6, 2013 - 02:13pm PT
My wife is between shoulder surgeries, right was done seven weeks ago, the left goes under in two weeks. She ices relentlessly and says it's the one thing that always works to calm the pain. We have three of the big Motion1 ice packs she rotates through icing about every 2-3 hours for ten minutes/shoulder and prefers them to the pumped shoulder icing system we also have.
moosedrool

Trad climber
lost, far away from Poland
Topic Author's Reply - Apr 6, 2013 - 02:22pm PT
Icing helps with the pain, but it may slow down healing.
orle

climber
Apr 6, 2013 - 02:37pm PT
Icing helps with the pain, but it may slow down healing.

Would it then help to go fasting?

BTW I take pregabalin daily, used to take 600mg a day, now down to 300mg. I'm still tapering off, and I'm considering switching to (the supposedly weaker/milder) gabapentin instead.
Norton

Social climber
the Wastelands
Apr 6, 2013 - 05:41pm PT
I am going into the Hospital on Tuesday for spine surgery

two hour procedure to remove enough bone to allow some main nerves more freedom from being pushed on now by collapsing discs

I have been on spine injections and heavy pain pills for ten years

yes, narcotics do in addition to blocking pain also slow down the metabolism

and that means ya can't move your bowels very easily

what works is drinking a glass of Metamucil a day to add fiber

and taking two stool softeners a day



my adice is to choose your parents more carefully to eliminate genetic bad stuff

and of course, don't get old, just say no to aging
Big Mike

Trad climber
BC
Apr 6, 2013 - 06:23pm PT
Good luck norton!!

Wishing you the best!! Let us know how it turns out please!
moosedrool

Trad climber
lost, far away from Poland
Topic Author's Reply - Apr 6, 2013 - 06:30pm PT
Good luck Norton!
donini

Trad climber
Ouray, Colorado
Apr 6, 2013 - 06:42pm PT
That stuff makes me drool.
Naitch

climber
Seneca area
Apr 6, 2013 - 06:50pm PT
Hey I dont need anything to make me drool.

All the best Norton...
kennyt

climber
Woodfords,California
Apr 6, 2013 - 06:55pm PT
Another unfortunate side effect.....


















Credit: kennyt
moosedrool

Trad climber
lost, far away from Poland
Topic Author's Reply - Apr 6, 2013 - 07:10pm PT
Kenny don't post the pics of me, please.
donini

Trad climber
Ouray, Colorado
Apr 6, 2013 - 07:12pm PT
That's the after shot.
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