My regret is that I spent too much time climbing, and not enough time doing other things like exploring the world; and now I am too injured to do either.
Relationships suffered because of my "passion".
I don't really have any regrets. Sure, some things could have worked out differently but in the end I am pretty satisfied with what I've done. I spent my youth surfing and water skiing and racing motorcycles in the dirt. Then I found climbing! I have made some great friends and had some awesome adventures climbing. I have climbed harder than I probably had any right to. I have been extremely lucky in who I ended up with as partners who were bold and skilled enough to do some fabulous stuff.
I could regret losing my 40s to health problems but when they got solved I was granted over a decade to make up for lost time where my strength, health and enthusiasm were just about unlimited and was able to enjoy another careers worth of hard climbing.
Now that I have sufficiently abused my upper body climbing hard thru my 50s and into my 60s I have found that my lower body actually still works really well and I am enjoying the desire to walk long distances into the hills!