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zBrown

Ice climber
Mar 21, 2019 - 08:39pm PT
Sensory hair cell loss is the major cause of hearing and balance disorders. Mammals are incapable of sustained hair cell regeneration, but lower vertebrates can regenerate these mechano-electrical transducers. We present the first comprehensive transcriptome (by mRNA- Seq) of hair cell regeneration in the chick utricle. We provide pathway and pattern annotations and correlate these with the phenotypic events that occur during regeneration


I was OK to here

It quickly becomes a morass of terms and processes we know nothing about


ROADHOUSE BLUES - Death of a Gremmie Version


Haven't even been ice skating.

Ever wonder how 17 years of your life can just have disappeared (that's nearly 24%).

In the service of good?

At least I didn't get me knees whacked.


[Click to View YouTube Video]
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 21, 2019 - 08:41pm PT
Hey there, say Zay...
Suck it up, big boy.

Many excuses for not doing routes
Like, "Oh, man, I forgot my damn boots."
etc.

Whitey: "Drizzle drazzle druzzle, Drone. Time for us to head back home."
Drone: "It stopped raining, Mike."

edit--zBrown, I thought I was reading the hard part!
zBrown

Ice climber
Mar 21, 2019 - 10:47pm PT
Putting it here so I do not lose it

But thanks to the mouse family for participating

The study breaks new ground because researchers developed a novel drug-delivery method. Specifically, it targets the cochlea, a snail-like structure in the inner ear where sensitive cells convey sound to the brain. Hearing loss occurs due to aging, working with noisy machines and too many loud concerts. Over time, hair-like sensory cells and bundles of neurons that transmit their vibrations break down, as do ribbon-like synapses, which connect the cells.

The researchers designed a molecule combining 7,8-dihydroxyflavone, which mimics a protein critical for development and function of the nervous system, and bisphosphonate, a type of drug that sticks to bones. The pairing of the two delivered the breakthrough solution, the researchers said, as neurons responded to the molecule, regenerating synapses in mouse ear tissue that led to repair of the hair cells and neurons, which are essential to hearing.
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 21, 2019 - 10:59pm PT
full moon and spring buds on sycamore tree
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 21, 2019 - 11:27pm PT
Amy Wineglass couldn't carry this off. She dead.
[Click to View YouTube Video]
What really rings your bell?
What resonates most with you?

Really? You're asking?

How about the plight of caged animals in a cage.
I shed a tear for all the dead lab mice.
Home Anne, I sometimes get in a rage!
7,8 DHF biphosphonate is not very nice.

But it's for science.🤔
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 21, 2019 - 11:30pm PT
Bill D. Nye, the other science guy, on the rocks.

Known as a very hip belayer.Butt bag, no harness, ancient rope pattern.

Smokin' a Mammut cheroot, there, Doc? Rope, get it?
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 22, 2019 - 06:00am PT
I'm glad to report that it seems Larry Jones is more mobile...he had hip replacement done and it is still early days.

He's outside taking pix and getting about better, it seems.

And I thank you for them, old pal.


I've been reminiscing now and again about 45 years ago in late March when Doug Ross and I joined up to climb the Big Stone.

It's been awesome living to see what Alex Honnold and Hans and Gobright and Caldwell and Florine and the Hubers and all the rest have accomplished since.

The biggest contrast has to be the style...all free or go home.

The huge style gulf between Piton Pete and Alex Honnold is like the one separating Mar a Lago from the Mexican ice cream vendor on a tricycle.

My biggest regret is that THERE ARE NO PIX of the Salathe nor of NWFHD--a pity, what?

Not that we were that photogenic nor were our deeds heroic or even above average, but, you know, for keepsakes...for the shoe box.
Gnome Ofthe Diabase

climber
Out Of Bed
Mar 22, 2019 - 06:21am PT
Ah yes the shoe box
The cardboard receptacle of memories
As full as we make it
the plight of not enough old pictures
that would show the back drop
that chapter the verses of our life

What No Me?










Do not, yos

your memories, mite

that faded now

very much fleeting

like dreams of fancy

dreams that might

retake us to the heights

return us in our vast minds

to the snail eye we might have had

but still make us feel the thrill

of those great feats














As a test, the test wasn't necessary

I already knew Rad as I was
I am not so rad any more

When I get to go to a show

the result

is yup
,Garble base

1st, lucid sour grapes
the fact is that the paradox that the Mohonk Preserve is
A on going take it all & Beyond ~ land grab

well, it is a nice story but has no basis in the facts of why the Smiley family established the Trust.
The Good intentioned Raubenheimer, with the onset of his own
family/children established the framework 1959-63,
to ensure 88% vs 12%, never allowed to grow to 20%
Won't/can't remember* the other names....
the Bad & the Ugly ad-hoc-group abusers
(Libraries, friends of,Associations, historical societies, climbers, others from one of a kind places,, Clove Valley road prop owners)
These Nyc Lawyers/criminals (hope that they are now dead)
who with *dis bar'd Suyveor Killmier, stole land
using fraudulent title/deed & manipulations(Fink/Pardini, +. et:al)
This; as much to grow/maximize the monetization of the holdings,
as to remove the threat of devaluation through any/all future use & development.
And then
yup-sters the way the corrupt is working

the fix is in

worst

The distorter of truth,

The loser will win

the grabber, divider & Thief will waltz

A thought
not beyond hope
that Im sufferin another break
Bat signal blew it is true
& I got go

went `cause we had on demand hot water again
the heater replaced

scary I'd like to show what the cob job looks like
I don't have your Email Z
eek its PHIL LESH
is that allowed on this thread?
[Click to View YouTube Video]
I think I should
you dont hack around and would beat me at HORSE
everytime.


& TOO See it while A (~);= it is not me That EyesOfTheWorld

STRANGE DAYS 'ROUND THE PLACE
ICE THREAD & A
nEMISIS SWOON;D

i'M NOT ADDING TO DUMPSTER FIRES

The Barr The Attorney General
The pardon'em guy cut the funding.

the trick

so Mueller tried to send the high salaried home

that got under the skin the funding was pulled
payed through today 3/22/19

the fix is in




For me 15th&16th
6 years & 2 daze to the day I dropped
a year later I drop here
return to sender rurp belay iz sloaper
its not worth it for me to play
sorry


mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 22, 2019 - 06:45am PT
"Make America White Again," is what the nationalistic bastards really want.

Don't be food. Be your predator self when staring these as#@&%es down.

Shithole rhetoric don't make it.

Trump is embarrassingly un-cool. Forget hip.[Click to View YouTube Video]

What was hip in '72-'73-'74-'75 in the Bay Area was about the same as in Miami is how it seems to me.

The whole place became hipper than possible in Berkeley in comparison to living in the City. But the Palo Alto crowd? Meh. Dilettantes when it came to protest and change. They had the Dead. Big deal.

The City folk were cool, no question. Peggy and Throwpie lived there for a time before migrating to Berkeley. My lady worked in the City for Cost+, but found it was better in the East Bay, Jack London Square.

JLS is very near the Oakland Coliseum, home of the World Champion A's and it doesn't get much hipper unless you pile on an NFL Super Bowl championship and an NBA title for the Bay Area at the same time.

In Berkeley the puka shell necklace (coral bits optional but hip) and loose full-sleeved shirt (head band for formal wear) and MAYBE a gold chain. NOT LOADED WITH BLING! Did we even call it bling back then? Can't recall.

But I'm a Berkeley/Merced centrist...you have a different perspective, natch.

And I'm just maundering...such an old fool.
[Click to View YouTube Video]Acquaintance with the music of Frank Zappa was hipster platinum, while no one but we Flames were listening to Captain Beefheart. Frank, of course, was more commercially potent, but that's relative, too. The Dead made more money, surely. I mean, that's why we do music, right? The bucks.

We still get sick from watchin' our teevee
Trouble comin' every day, No way to delay it

Stomp and smash and crash and slash and bust and burn

This may be overplayed. So it goes. But there's only one way out. Get rid of the bozo driving the bus.
[Click to View YouTube Video]Throw him under the bus, someone, please!
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 22, 2019 - 06:56am PT
Possibly the most hip occurrence in Yosemite history.
https://www.reddit.com/r/todayilearned/comments/8bvhb5/til_that_a_plane_carrying_6000_pounds_of_pot/

I can't imagine all that scrambling and energy wasted on recovering three tons of puka shells.

Pretty obvious, just sayin'--maunder maunder
[Click to View YouTube Video]At the apex of his game.

[Click to View YouTube Video]Working well together, real journeymen.
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 22, 2019 - 08:24am PT
Center, bunhead, breathe...and center.

Be wherever, but be here now.

In the middle.
[Click to View YouTube Video][Click to View YouTube Video]
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 22, 2019 - 08:34am PT
[Click to View YouTube Video]This is good stuff.

I'm wonderin' how Dick Dale would have done this.
Sure he could. Double-pickin' was no thing for him.
We'll never know. You probably never cared.

Hi ho.

Don't you cry for Dick.[Click to View YouTube Video]
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 22, 2019 - 09:17am PT
Apropos of nada, it just sounds cool to say,

"The problem with being empathetic--you feel sorry for a-holes, too."
There's Kamps himself. Thank you Bonnie for posting these.
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 22, 2019 - 03:57pm PT
Justice Just Is
A special report from the Congressional Hearings
On Malfeasance and Shenanigans at The Very Top

Being a trained investigator, I smelled a rat.

This Bozo was not shooting straight.

Also, being a trained psychologist and gunsmith,
I could tell beyond question that he was a few
rounds short of a full mag.

He was up there blowing smoke,
and the committee wasn't really buying it.

Give them credit, they seemed to have it all
sewn up--and then the special prosecutor
called him to testify.

So he swore an oath. (Smirking here.)

He is not up there telling harmless white lies,
my friends.

He is creating some orange whoppers which will no
doubt be backed up by rumors, tweeted "facts," and
the shifting of blame elsewhere besides at the door
to the Offal Orifice.

He will likely mislead and misdirect and it will drag
on and on and soon he'll be gone, if fate so decides.

Until then, or whenever,
"Can I get cheese on those Whoppers, Mr. Rat?"

Sidebar for Miss Molly--
Oh, how sorry I am for you to have to get
permission from this vermin to marry a frog.

He doesn't like the idea you're marrying a foreigner,
I know.

Good luck.

You guys should move away from that swamp, I'm tellinya.

Mouse

edit: claiming literary license for changing the
tale of Froggy and Miss Molly.
Gnome Ofthe Diabase

climber
Out Of Bed
Mar 22, 2019 - 07:24pm PT
Kinda My Kind `a Gal: At least a survivor smiling biggly after all That's harding to look at

That right there is A fishy post,( z? )

I don't mean to be overtly judgemental,

And meant in jest (meany & cruel), but remember the chant?

Where all the too cute by half and then some
Cheerleader girls who were barely dressed, would lead
While provocatively Swinging & shaking their assets
 harmonizing, viciously chanting in unison;
(thats what harmonizing is)

U. G. L. Y. You ain't got no alibi - you ugly,

Delivered in rapid staccato, repeated three times for full effect,,,
as the rock got passed up-court by boys in short shorts?
It was a part of growing up in the Jock world. It was harsh...


booy sheesh ugli she's ugli
and she ain't got no alibi sheesh-ugli



The Ice Is Nice especially on top rope or in that case on rappel
Both that & this were,
(what started as just the harsh headshot)
then a climber rapping in on a short ice column,
(now the whole post is gone)
 gone? So gnome restored
apparently less than likable 'round here'bouts
-bout `er upside the leg...

yuk-yuk-yuk



a share to far maybe?
it remains just a picture of an aged smiling,
she is ~ smiling? Tonya Harding



followed by a Phish share ! !

Not "Sugar Shack"

but at this Meuk-a-puke moment

as it is a song that I like

the lyrics of which I'll also share here tonight

last played @ this 10/19/18 Hampton show (18 shows ago)

hear "Rift"

https://soundcloud.com/user-942682835/rift-2?in=user-942682835/sets/phish-live-at-hampton-coliseum-10192018-full-show-aud




Rift
Phish

Last night, in the moments my thoughts were adrift

And coasting a terrace, approaching a rift

Through which I could spy several glimpses beneath

Of the darkness the light from above could not reach

I spied wings of reason, herself taking flight

And upon yonder precipice saw her alight

And glared back at me one last look of dismay

As if she were the last one she thought I'd betray

So much better I said to myself

And drawing quite close to the top of the shelf

I struggled with destiny upon the ledge

And gasped when defeated he slipped off the edge

And silence contagious in moments like these

Consumed me and strengthened my will to appease

The passion that sparked me one terrible night

And shocked and persuaded my soul to ignite

So much…more
MOHR!
& Pleeze excuse but from 1987 Dylan/Dead tour
Just posted 3/16/19
With only 55 views so fresh With The Other Bob Too** [Click to View YouTube Video]

mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 23, 2019 - 08:16am PT
doggerel

she won't do what you want
won't heel at your behest
but when it comes to licking hands
our feisty pet's the best

her attitude is slightly rude
she's very picky 'bout her food
no pedigree--she's just a mutt
she loves us, though, no matter what

*yap-yap-yap*

*woof-woof-woof*

*woot-woot-woot*
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 23, 2019 - 08:39am PT
Again, il pleut owe jure dui.
[Click to View YouTube Video]I'll be on my way...
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 23, 2019 - 08:49am PT
I'm back. Like a homerun, I'm back back back.

Philosophizing about destiny, the origin of inspiration, and himself.
[Click to View YouTube Video]https://ny.curbed.com/2017/2/10/14579250/greenwich-village-vintage-photos-bob-dylan
As many changes as David Bowie.

It's a soft but toxic rain falling now and it is colored orange.
Rhyme me that, Bob.

Christian or Jew?There is no Jerusalembert Dome. Sorry.

[I noted that Ed Bradley mentioned in their innerview
that Dylan was nominated for the Nobel in Lit back then,
prior to his winning it just recently.]
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 23, 2019 - 09:19am PT
Ho-lee sh.t!

Better'n watchin' NASCAR, boy.

https://www.youtube.com/watch?v=Zh-GYMCOzOE
https://www.youtube.com/watch?v=6_r_iePbASw
mouse from merced

Trad climber
The finger of fate, my friends, is fickle.
Topic Author's Reply - Mar 23, 2019 - 09:59am PT
Of the Value of a Middle Name

gno·mon
/ˈnōmən/
noun
1.
the projecting piece on a sundial that shows the time
by the position of its shadow.
2.
GEOMETRY
the part of a parallelogram left when a similar parallelogram
has been taken from its corner.

"gnomon" is sometimes confused with "nomen"

no·men
/ˈnōmən/
noun
the second personal name of a citizen of ancient Rome,
indicating the gens to which he belonged,
for example, Marcus Tullius Cicero.

So, based on this research, our poster-boy for garblebase,
has a nomen, though he's not a Roman.

"Ofthe."

Were I a loyal Roman, with my three-part internet name,
I'd seek this surefire method to win eternal fame:

I'd gladly be a Roman senator, namely Mouse "from" Merced.
And I'd gladly bash our own "Caesar" upon his orange head.
I'd kick him when he'd fallen, and dance upon his grave,
For he's not a man to love, just a disgraced lying knave.


I don't know what prompts all this rage.
Maybe because DT's behavior is so outrageous?
Maybe cuz there are so many stoopid supporters who fall for his BS?
Maybe
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